| Catalog Number | NSJ-BC-008 |
| Category | TLR7/8 agonist |
| Sub-Category | Vaccine adjuvants |
| Therapeutic applications | Potent adjuvants for the induction of antigen-specific Th1 responses in an immune tolerant state |
| CAS No. | 1026249-18-2 |
| Chemical Name | 2-(Ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine |
| Chemical Formula | C13H14N4O |
| Synonyms | CL097 |
| Molecular Weight | 242.28 |
| Reference | 1. Wang, Y, et al, Immunizations with hepatitis B viral antigens and a TLR7/8 agonist adjuvant induce antigen-specific immune responses in HBV-transgenic mice, Int. J. Infect. Dis. 2014, 29, 31-36
2. Maalej, K. M, et al, The TLR7/8 agonist CL097 primes N-formyl-methionyl-leucyl-phenylalanine–stimulated NADPH oxidase activation in human neutrophils critical role of p47phox phosphorylation and the proline isomerase pin1, J. Immunol. 2012, 189, 4657-4665 |
