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1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine

1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine

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 Catalog Number NSJ-BC-005
Category TLR7/8 agonist
Sub-Category Vaccine adjuvants
Therapeutic applications Anticancer
CAS No. 1258457-59-8
Chemical Name 1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine
Chemical Formula C22H25N5
Synonyms IMDQ
Molecular Weight 359.48
Reference 1. Yoo, E, et al, Hyaluronic acid conjugates of TLR7/8 agonists for targeted delivery to secondary lymphoid tissue, Bioconjugate Chem. 2018, 29, 2741−2754.

2. Vrieze, J. D. et al, Potent lymphatic translocation and spatial control over innate immune activation by polymer–lipid amphiphile conjugates of small-Molecule TLR7/8 agonists Angew. Chem. Int. Ed. 2019, 58, 15390 –15395.