| Catalog Number | NSJ-BC-002 |
| Category | TLR7/8 agonist |
| Sub-Category | Vaccine adjuvants |
| Therapeutic applications | Anticancer, adjuvant for pandemic influenza vaccines |
| CAS No. | 1359993-59-1 |
| Chemical Name | N-(4-((4-Amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)oxy)butyl)stearamide |
| Synonyms | MEDI9197, Telratolimod, 3M-052 |
| Chemical Formula | C36H59N5O2 |
| Molecular Weight | 593.47 |
| Reference | 1. Hoeven, N. V. et al, A formulated TLR7/8 Agonist is a flexible, highly potent and effective adjuvant for pandemic influenza vaccines, Scientific reports 2017, 7, 46426. 2. Smirnov, D. et al, Vaccine adjuvant activity of 3M-05
2: An imidazoquinoline designed for local activity without systemic cytokine induction, Vaccine, 2011, 29, 5434- 5442. |
